胰岛瘤在胰岛细胞肿瘤中最为常见,日本报道超过260例。本文通过回顾性及随访研究确定胰岛瘤最可靠的综合诊断方法并选择最恰当的外科处理方式。本研究分析为日本东北大学医学院收治的胰岛瘤22例(男10例,女12例),年龄19～70岁,平均45岁。各例均有不同程度的低血糖症,并经手术治疗,计胰腺远段切除17例(包括2例盲目性),肿瘤摘出术4 Insulinoma is most common in islet cell tumors, and more than 260 cases have been reported in Japan. This article through retrospective and follow-up studies to determine the most reliable comprehensive diagnosis of insulinoma and select the most appropriate surgical treatment. This study analyzed 22 insulinoma cases (10 males and 12 females) admitted to the Tohoku University School of Medicine in Japan, aged 19 to 70 years with an average of 45 years. All cases had varying degrees of hypoglycemia and were treated surgically. 17 cases (including 2 cases of blindness) of distal pancreatic resection were enrolled.