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作者研究了长期口服圣罗勒Ocimumsanctum L.鲜叶是否对心脏中一些重要的内源性抗氧剂的基础水平和由异丙肾上腺素(ISO)诱发的小鼠心肌坏死有影响。圣罗勒鲜叶在双蒸水中研磨成组织匀浆,以50和100mg/kg2种剂量管饲法给以Wistar大鼠,每天1次,共30天。对照组喂饲生理盐水30天。30天后2个给药组均皮下注射ISO 85mg/g2次(间隔12h)。给药结束
The authors investigated whether long-term oral administration of fresh leaves of Ocimumsanctum L. affects basal levels of some important endogenous antioxidants in the heart and myocardial necrosis in mice induced by isoproterenol (ISO). Fresh leaves of St. Basil were ground into tissue homogenates in double distilled water and administered to Wistar rats twice daily for 2 days at 50 and 100 mg / kg gavage for 30 days. The control group was fed with normal saline for 30 days. After 30 days, the two administration groups were subcutaneously injected with ISO 85mg / g2 times (interval 12h). The drug is over