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目的探讨原发性肝癌术后经肝动脉化疗栓塞对患者复发率及生存率的影响。方法对2003年至2006年本院行肝癌切除术后的156例患者,按术后1个月左右是否补充介入治疗分为TACE组(88例)和对照组(68例),对比分析两组患者术后1、2、3年的累积复发率和生存率。结果TACE组1、2、3年的累积复发率分别为12.1%、48.6%、74.6%,累积生存率分别为83.0%、72.8%、63.2%;对照组1、2、3年的累积复发率分别为46.9%、65.5%、82.7%,累积生存率分别为72.6%、58.3%、51.0%。两组间比较差异有显著性(P<0.05)。结论术后予辅助性肝动脉化疗栓塞可降低患者复发率,延长生存期。
Objective To investigate the effect of transcatheter arterial chemoembolization on the recurrence rate and survival rate in patients with primary liver cancer after operation. Methods From 2003 to 2006, 156 patients with HCC after resection of liver cancer were divided into TACE group (88 cases) and control group (68 cases) according to the interventional treatment about 1 month after operation. Two groups were compared 1, 2, 3 years after the cumulative recurrence rate and survival rate. Results The cumulative recurrence rates at 1, 2 and 3 years in TACE group were 12.1%, 48.6% and 74.6%, respectively, and the cumulative survival rates were 83.0%, 72.8% and 63.2%, respectively. The cumulative recurrence rates at 1, 2 and 3 years Respectively 46.9%, 65.5% and 82.7%, and the cumulative survival rates were 72.6%, 58.3% and 51.0% respectively. The difference between the two groups was significant (P <0.05). Conclusion Postoperative adjuvant hepatic arterial chemoembolization can reduce the recurrence rate and prolong survival.