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精液是强碱性缓冲液。射精使阴道pH在数秒钟内由4.0～4.5上升至6.0～7.0,并维持数小时。在阴道被重新酸化之前,精子保持活力。如果酸性环境能在足够短的时间内使精子失活,那么使阴道在射精时仍保持酸性的物质可用于避孕。本文测试并比较了弱酸和缓冲胶使精子去活和死亡以及胞外弱酸影响胞质pH的速率。
Semen is a strong alkaline buffer. Ejaculation causes the vaginal pH to rise from 4.0-4.5 to 6.0-7.0 within a few seconds and is maintained for several hours. Sperm remain viable before the vagina is re-acidified. If the acidic environment inactivates sperm in a sufficiently short period of time, then the vagina remains acidic during ejaculation can be used for contraception. This article tests and compares the rates of deactivation and death of sperm by weak acids and buffer gums and the effect of extracellular weak acids on the pH of the cytoplasm.