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目的:探讨不同季节性气候条件下正常妊娠和子痫前期孕妇的血液流变学变化。方法:检测150例正常妊娠和120例子痫前期孕妇的血液流变学指标,同时根据传统节气将正常妊娠和子痫前期孕妇分为夏季组、冬季组和过渡季组,比较不同组间正常妊娠和子痫前期孕妇的血液流变学变化。结果:与过渡季组相比,正常妊娠妇女冬季组的全血黏度(1/s、5/s)呈升高趋势(P<0.05);与夏季组和过渡季组比较,正常妊娠妇女冬季组的全血黏度(30/s、200/s)升高,但差异无统计学意义(P>0.05);与过渡季组和冬季组比较,正常妊娠妇女夏季组的血浆黏度升高(P<0.05);与过渡季组比较,正常妊娠妇女夏季组和冬季组红细胞聚集指数升高(P<0.05);与夏季组比较,正常妊娠妇女冬季组的红细胞压积升高(P<0.05);夏季组及冬季组子痫前期孕妇的全血黏度(1/s、5/s、30/s、200/s)呈升高趋势,与过渡季组比较,冬季组低切(1/s、5/s)全血黏度显著升高(P<0.05);冬季组子痫前期孕妇的红细胞压积值较夏季组和过渡季组显著升高(P<0.05)。结论:寒冷季节正常孕妇血液有浓缩倾向,冬季子痫前期孕妇全血黏度增高更明显,可能是寒冷季节子痫前期发病率增多、并发严重病例增加的病理生理基础。
Objective: To investigate the hemorrheological changes of pregnant women and pregnant women with preeclampsia in different seasonal climates. Methods: The hemorrheological indexes in 150 normal pregnant women and 120 pregnant women with preeclampsia were detected. At the same time, normal pregnant women and pregnant women with preeclampsia were divided into summer group, winter group and transitional group according to the traditional method. Hemorheological changes in pregnant women with preeclampsia. Results: Compared with the transitional group, the whole blood viscosity (1 / s, 5 / s) of the normal pregnant women showed an increasing trend (P <0.05) compared with the transitional group. Compared with the summer and transitional groups, (P> 0.05). Compared with the transitional group and the winter group, the plasma viscosity of normal pregnant women increased in the summer (P <0.05) (P <0.05). Compared with the transitional group, the normal pregnant women increased the hematocrit index in both summer and winter groups (P <0.05). Compared with the summer group, the normal pregnant women increased the hematocrit in the winter group (P <0.05) . The whole blood viscosity (1 / s, 5 / s, 30 / s, 200 / s) of pregnant women in preeclampsia of summer group and winter group showed an increasing trend. Compared with the transitional group, (P <0.05). The hematocrit values of pregnant women in preeclampsia group were significantly higher than those in summer and transitional seasons (P <0.05). CONCLUSION: Normal pregnant women tend to concentrate in the blood in the cold season, and the increase of whole blood viscosity in pregnant women with preeclampsia in winter is more obvious. This may be the pathophysiological basis for the increased incidence of preeclampsia and severe cases in the cold season.