脑组织移植的研究已有整整一个世纪的历史。早在1890年,Thompson 就在纽约医学杂志上发表了题为“成功的脑移植”的报告,他将成年猫和狗的大脑皮层组织分别移植到成年狗的大脑皮层,2周后切片在显微镜下观察到移植块内大部分组织已坏死,但有少量移植的神经元存活。Saltykow(1905)行幼兔大脑皮层移植,移植物存活8天。Del Conte(1907)首次试图将哺乳动物(兔)胚胎脑组织作 Brain tissue transplantation has been a century-old history. As early as 1890, Thompson published a report entitled “Successful Brain Transplantation” in the New York Medical Journal. He transplanted adult cats and dogs’ cortical tissues into the cortex of adult dogs respectively. Two weeks later, they were sectioned in a microscope It was observed that most of the tissue in the graft was necrotic, but a small amount of transplanted neurons survived. Saltykow (1905) performed rabbit cerebral cortex transplantation for 8 days. Del Conte (1907) first attempted to make mammalian (rabbit) embryonic brain tissue