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氟中毒是因为过量摄入氟进入人体后引起的一种慢性全身性疾病该疾病早期表现为食欲不振、疲乏无力、头晕头痛。过量氟进入人体后主要沉积在牙齿和骨骼上,所以氟中毒是以骨骼损伤最为严重。1对象与方法选用SPF及Wistar大鼠40只,由北京维通利华实验动物中心提供,体重在120~140 g之间,雌雄各半,年龄为3~4月周龄。将大鼠随机分为4组,各10只。分别为对照组、高剂量氟中毒组、中剂量氟中毒组、低
Fluorosis is a chronic systemic disease caused by excessive intake of fluoride into the body. The disease manifests itself as an early loss of appetite, fatigue, dizziness and headache. Excessive fluorine into the body after the main deposition in the teeth and bones, so fluorosis is the most serious bone damage. PARTICIPANTS AND METHODS One hundred and forty SPF and Wistar rats were selected and provided by Beijing Vital Center for Experimental Animals, weighing 120-140 g and male and female respectively, ranging in age from 3 to 4 weeks. The rats were randomly divided into 4 groups, each 10. Respectively, the control group, high-dose fluorosis group, medium-dose fluorosis group, low