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目的对比分析应用炔雌醇环丙孕酮片(达英-35)与去氧孕烯炔雌醇片(妈富隆)治疗青春期多囊卵巢综合征的临床效果。方法 142例青春期多囊卵巢综合征患者,随机分为达英-35组和妈富隆组,每组71例。达英-35组给予达英-35进行治疗,妈富隆组给予妈富隆治疗,对比分析两组患者的治疗效果。结果达英-35组治疗前黄体生成素(LH)为(15.82±5.36)m IU/ml,治疗后LH为(7.03±2.15)m IU/ml;妈富隆组治疗前LH为(15.33±5.89)m IU/ml,治疗后LH为(6.02±2.35)m IU/ml,治疗后两组LH水平显著优于治疗前,且达英-35组优于妈富隆组(P<0.05)。达英-35组治疗前血睾酮(T)为(1.30±0.48)ng/ml,治疗后血T为(2.0.36±0.17)ng/ml;妈富隆组治疗前血T为(1.37±0.57)ng/ml,治疗后血T为(0.85±0.24)ng/ml,治疗后两组血T水平显著优于治疗前,且达英-35组优于妈富隆组(P<0.05)。结论达英-35治疗青春期多囊卵巢综合征效果更显著,可以有效的缓解临床症状、降低异常增高激素,值得推广使用。
Objective To compare and analyze the clinical effect of ethinylestradiol and cyproterone tablets (Da Ying-35) and desogestrel ethinyl estradiol tablets (Marvelon) in the treatment of adolescent polycystic ovary syndrome. Methods 142 cases of adolescent polycystic ovary syndrome patients were randomly divided into da-Ying-35 group and Marvelon group, 71 cases in each group. Up to -35 group was given up to Ying -35 for treatment, Marvelon group Marvelon treatment, comparative analysis of two groups of patients with treatment. Results The LH of LH-35 group was (15.82 ± 5.36) m IU / ml before treatment, and (7.03 ± 2.15) m IU / ml after LH treatment. LH was (15.33 ± 5.89) ), mU / ml, LH after treatment was (6.02 ± 2.35) mIU / ml. After treatment, the levels of LH in both groups were significantly better than those before treatment, and those in Ying-35 group were better than those in Marvelon group (P <0.05). The blood T (T) of up to -35 group was (1.30 ± 0.48) ng / ml before treatment and the blood T was (2.0.36 ± 0.17) ng / ml after treatment; the blood T before treatment was 1.37 ± 0.57 ) ng / ml. After treatment, the blood T level was (0.85 ± 0.24) ng / ml. After treatment, blood T levels in both groups were significantly better than those before treatment, and those in Yingying-35 group were better than those in Marvelon group (P <0.05). Conclusion Da-Ying-35 treatment of adolescent polycystic ovary syndrome effect is more significant, can effectively alleviate the clinical symptoms and reduce abnormal increase hormone, it is worth promoting the use of.