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复方磺胺甲异噁唑(Co-trimoxazole,复方SMZ)是由SMZ和TMP组成,体外试验表明,在最佳浓度比(1:10～1:40)时,两药可发生协同作用。但研究表明,使用复方SMZ后,尿液、支气管吸出液和脑脊液中两药浓度并不能达到最佳比例。最近又引进了
Co-trimoxazole (SMZ) is composed of SMZ and TMP. In vitro experiments show that the two drugs can have a synergistic effect at the best concentration ratio (1:10 ~ 1:40). However, studies have shown that the use of compound SMZ, urine, bronchial aspirate and cerebrospinal fluid concentration of the two drugs and can not achieve the optimal ratio. Recently introduced