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本文目的在于探讨心衰时血浆心钠素和微量元素二者之间的内在联系和相互作用,以便为一些常见心血管疾病的防治提供科学依据。材料与方法:①动物:家兔11只,雌雄不拘,体重1.9～2.7公斤,颈部与胸部脱毛。②心衰前:停止呼吸,用RM-46四导生理记录仪同步记录心电、心音、阻抗。股动脉采血测定血清四种微量元素和血浆ANP。③心衰后:用戊巴比妥钠麻醉家兔,当心脏重度抑制,舒张期奔马律,心室自博心律,股动脉取血测定ANP与微量元素。④血浆ANP测定:采用快速放免分析法,⑤心房ANP测
The purpose of this paper is to explore the intrinsic relationship and interaction between plasma atrial natriuretic peptide and trace elements in heart failure so as to provide a scientific basis for the prevention and treatment of some common cardiovascular diseases. Materials and Methods: ① Animals: Rabbits 11, male and female, weight 1.9 ~ 2.7 kg, hair removal of the neck and chest. ② heart failure before: stop breathing, with RM-46 four-channel physiological recorder simultaneously record ECG, heart sounds, impedance. Femoral Artery Blood Determination of four trace elements and plasma ANP. ③ heart failure: rabbits anesthetized with pentobarbital sodium, when severe cardiac arrest, diastolic gallop, ventricular self-Bo heart rhythm, femoral artery blood and ANP determination of trace elements. ④ plasma ANP determination: fast radio immunoassay, ⑤ atrial ANP measurement