临床上常联合应用两种或两种以上抗菌药物 ,利用药物间的协同作用增加疗效。联合用药可能发生的结果 :抗菌药物联合在体外或动物实验中可以获得“无关”、“累加”、“协同”和“拮抗”作用。“无关”作用指总的作用不超过联合中较强者。“累加”作用指两种药物联合相当于相加? Clinically often combined with two or more antibacterial drugs, the synergy between drugs to increase efficacy. Possible outcomes of combination therapy: Antimicrobial combinations can achieve “irrelevant”, “additive”, “synergistic” and “antagonistic” effects in in vitro or in vivo experiments. The “unrelated” effect means that the total effect does not exceed the stronger one in the union. “Accumulation” refers to the combination of two drugs equivalent to add?