急性有机磷农药中毒是常见的急诊之一,由于中间综合征(Intermediate syndrome,IMS)发生后,阿托品及胆碱脂酶复能剂对其疗效不佳,未获及时诊断和抢救的患者常因呼吸肌麻痹、呼吸衰竭而死亡,故应引起临床工作者的高度重视。现将我院收治的4例IMS患者报告如下。1 临床资料1.1 一般资料 1993年3月～1999年3月我院急诊科共收治经口服有机磷农药中毒患者53例,其中发生IMS4例,发生率为同期入院的急性有机磷农药中毒患者人数的7.5%。男1例,女3例,年龄18～25岁,平均21.6岁。服毒剂量20～100 Acute organophosphorus pesticide poisoning is one of the common emergency cases. Because of the poor response of atropine and cholinesterase agents after intermediate syndrome (IMS), patients often fail to get timely diagnosis and rescue Respiratory muscle paralysis, respiratory failure and death, it should be caused by clinicians attach great importance. Four cases of IMS patients admitted to our hospital are as follows. 1 Clinical data 1.1 General Information March 1993 ~ March 1999 emergency department admitted to our hospital were treated with oral organophosphate pesticide poisoning in 53 patients, of which IMS4 occurred, the incidence rate for the same period the number of patients admitted to acute organophosphorus pesticide poisoning 7.5%. 1 males and 3 females, aged 18 to 25 years, an average of 21.6 years old. Toxic dose 20 ~ 100