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目的:探讨云南白药促进宫颈上皮内瘤变宫颈冷刀锥切术后康复的疗效。方法:96例宫颈上皮内瘤样病变(CINⅢ级)宫颈冷刀锥切术(CKC)术后,随机分为观察组和对照组各48例。对照组CKC术后创面电灼后纱条填塞并常规抗感染治疗4 d;观察组创面电灼后用云南白药粉覆盖创面后纱条填塞,常规抗感染治疗4 d,云南白药胶囊口服,2粒/次,tid,疗程5 d。观察术后1,2,5,8周阴道排液时间及排液量,阴道出血时间及出血量,宫颈痂膜脱落情况及其宫颈创面伤口愈合情况。结果:观察组术后阴道流血时间及平均阴道流血量均少于对照组(P<0.01);观察组术后阴道排液时间及平均阴道排液量均少于对照组(P<0.01);观察组术后5周及8周分别有23例和45例创面愈合,均优于同期对照组的12例和34例(P<0.05);术后5周观察组阴道清洁度明显优于对照组(P<0.01);两组术后疗效差异不明显。结论:CINⅢ级患者在CKC术后采用电凝止血并以云南白药粉覆盖创面,并配合云南白药胶囊内服,减轻了术后并发症,促进了疾病的康复。
Objective: To explore Yunnan Baiyao promote cervical intraepithelial neoplasia after cervical cold knife conization after curative effect. Methods: 96 cases of cervical intraepithelial neoplasia (CIN Ⅲ grade) cervical cold knife conization (CKC) were randomly divided into observation group and control group of 48 cases. The wounds of the control group were treated with wound dressing and conventional anti-infective therapy for 4 days. The wounds in the observation group were treated with Yunnanbaiyao powder after covering the wounds, and were treated with conventional anti-infective therapy for 4 days. The Yunnan Baiyao capsule was orally administered 2 Grain / time, tid, treatment 5 d. One, two, five and eight weeks postoperative vaginal discharge time and fluid volume, vaginal bleeding time and bleeding volume, cervical crustal shedding and wound healing of cervical wounds. Results: The time of vaginal bleeding and the average amount of vaginal bleeding in the observation group were less than those in the control group (P <0.01). The time of vaginal discharge and the average volume of vaginal discharge in the observation group were less than those in the control group (P <0.01). In the observation group, 23 cases were cured at 5 weeks and 45 cases at the 8th week respectively, which were better than those in the control group at 12 and 34 cases (P <0.05). The vaginal cleanliness of the observation group was significantly better than that of the control group Group (P <0.01). There was no significant difference between the two groups in postoperative efficacy. CONCLUSION: CIN Ⅲ patients are treated with electrocoagulation and hemostasis after the operation of CKC, and cover the wound with Yunnanbaiyao powder. Combined with Yunnanbaiyao capsule, it can reduce postoperative complications and promote the recovery of the disease.