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目的探讨不同手术方式对手术病理分期Ⅰ期子宫内膜癌预后的影响。方法收集129例手术病理分期Ⅰ期子宫内膜癌患者的临床病理资料进行回顾性分析。随访50例全子宫或者广泛(次广泛)切除、双附件切除患者(A组)和79例全子宫或者广泛(次广泛)、双附件切除及盆腔淋巴结清扫患者(B组)。分别对患者生存率及复发率进行统计分析。结果 129例随访率99.2%,5年总生存率为84%,A、B两组患者术后5年生存率分别为79%、87%。术后复发13例(A组9例,B组4例),A、B两组患者术后复发率分别为18%(9/50)、5.1%(4/79)。两组生存率、复发率比较差异显著(P<0.05)。结论手术病理分期Ⅰ期高危患者,盆腔淋巴清扫术能提高生存率,降低复发率。
Objective To investigate the effect of different surgical methods on the prognosis of stage Ⅰ endometrial carcinoma in surgical pathology. Methods The clinical data of 129 patients with stage Ⅰ endometrial cancer undergoing surgical pathology were retrospectively analyzed. All patients were followed up for 50 cases of total uterus or extensive (sub-wide) resection, double-attachment resection (group A) and 79 cases of whole uterus or extensive (sub-extensive), double attachment resection and pelvic lymph node dissection (group B). Respectively on the survival rate and recurrence rate of statistical analysis. Results The follow-up rate of 129 cases was 99.2% and the 5-year overall survival rate was 84%. The 5-year survival rates of patients in group A and B were 79% and 87%, respectively. Postoperative recurrence occurred in 13 cases (9 cases in group A and 4 in group B). The recurrence rates in group A and B were 18% (9/50) and 5.1% (4/79) respectively. The survival rate and recurrence rate of the two groups were significantly different (P <0.05). Conclusions Stage Ⅰ high-risk surgical pathology staging, pelvic lymphadenectomy can improve the survival rate and reduce the recurrence rate.