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本文报道昆明山海棠对人外周血淋巴细胞的染色体畸变效应测试结果。分别将昆明山海棠根部水提物（ＴＨＨ）５０、１００、２００、４００、８００μｇ／ｍｌ和乙醇提到物（ＡＴＨ）２５、２５、５０、１００和２００μｇ／ｍｌ进行人外周血淋巴细胞染色体畸变试验，均未显示明显的染色体畸变作用。空白和溶剂对照组的染色体无异常，阳性对照组的染色体畸变率为３９％，显示明显的诱变作用。结果表明昆明山海棠两种提取物在本试验的剂量范围内，对人外周血淋巴细胞染色体无致畸变作用
This article reports the test results of the effect of chromosome aberration on human peripheral blood lymphocyte in Begonia tuberosum. Human peripheral blood lymphocytes (PBMCs) were isolated from 50, 100, 200, 400, 800μg / ml and ATH 2.55, 25, 50,100 and 200μg / Chromosome aberration test, did not show significant chromosomal aberrations. Chromosomes in the blank and solvent control groups were normal, and the chromosome aberration rate in the positive control group was 39%, indicating a significant mutagenic effect. The results show that both extracts of Begonia tuberosus have no deleterious effects on the chromosome of human peripheral blood lymphocytes in the dose range of this experiment