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用简易的髓鞘碱性蛋白(MBP)酶联免疫吸附定量测定(ELISA)法对40例中枢神经系统感染患儿进行检测,其中病毒性脑炎15例,脑膜脑炎12例,化脓性脑膜炎13例,同时与对照组(无神经系统疾病)40例相比。结果显示:病毒性脑炎(脑膜脑炎)组、化脓性脑膜炎组血清MBP含量均较对照组高,有显著性差异(P<0.001),病毒性脑炎组亦比化脓性脑膜炎组高,差异显著(P<0.01),且血清MBP的含量与病情及病损范围呈正相关。
Forty patients with central nervous system infection were detected with simple MBP enzyme-linked immunosorbent assay (ELISA), including 15 viral encephalitis, 12 meningoencephalitis, purulent meningitis Inflammation in 13 cases, at the same time with the control group (no neurological disease) compared to 40 cases. The results showed that serum MBP levels in viral encephalitis (meningoencephalitis) group and purulent meningitis group were significantly higher than those in control group (P <0.001), and viral encephalitis group was also higher than that in purulent meningitis group High, the difference was significant (P <0.01), and the content of serum MBP was positively correlated with the extent of the disease and the lesion.