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目的在有或无疑似餐后低血糖症状的受试者中进行5小时口服葡萄糖耐量试验(5hOGTT),探讨OGTT特征及其临床应用价值。方法共纳入27例有疑似餐后低血糖症状的受试者和41例无餐后低血糖症状的受试者,均行82.5g葡萄糖的5hOGTT。结果在无餐后低血糖症状的受试者中共筛查出低血糖6例。在有疑似餐后低血糖的受试者中共筛查出低血糖17例,低血糖再现率83%。诊断服糖后低血糖的人群中IGT伴发率达30%。结论与无餐后低血糖症状人群相比,有疑似餐后低血糖人群中服糖后低血糖的发生率高达63%,服糖后低血糖病例的IGT伴发率达29%。对有疑似餐后低血糖病例进行4hOGTT低血糖筛查敏感性达100%。
Objective To investigate the characteristics of OGTT and its clinical value in subjects with or without postprandial hypoglycemia for 5 hours oral glucose tolerance test (5hOGTT). Methods A total of 27 subjects with suspected postprandial hypoglycemia and 41 subjects without postprandial hypoglycemia were included in the study. All patients received 82.5g of glucose for 5hOGTT. Results Six patients with hypoglycemia were screened out of subjects without hypoglycemia. In subjects suspected of postprandial hypoglycemia, 17 cases of hypoglycemia were screened, and the rate of hypoglycemia was 83%. IGT diagnosis in patients with hypoglycemia crowd up to 30%. Conclusions Compared with those without hypoglycemia, the incidence of hypoglycemia after hypoglycemia is as high as 63% in those with suspected postprandial hypoglycemia and 29% with hypoglycemia after taking sugar. Sensitivity to 4 hOGTT hypoglycemia screening for suspected postprandial hypoglycemia cases was 100%.