新型冠状病毒肺炎住院患者心电图表现分析

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目的:了解新型冠状病毒肺炎(COVID-19)住院患者体表心电图异常情况。方法:对2020年1月20日至3月1日武汉大学中南医院收治的147例COVID-19患者的入院及出院体表心电图进行回顾性分析,按照患者的临床分型分为轻型/普通型组及重型/危重型组,比较两组患者的临床资料、实验室检查结果及入出院体表心电图等指标。结果:147例COVID-19患者中,轻型/普通型患者123例,重型/危重型患者24例。与轻型/普通型患者相比,重型/危重型患者年龄较大,炎性指标及心肌酶学指标明显升高,且室性早搏(16.7%对4.7%)、QTc间期延长(4.2%对0)、异常Q波(4.2%对0)、胸前导联R波递增不良(4.2%对0)、胸前导联/肢体导联低电压(9.1%对0)等体表心电图异常表现比例更大(n P均<0.05)。n 结论:重型/危重型COVID-19患者更容易出现体表心电图异常包括室性早搏、QTc间期延长、异常Q波、胸前导联R波递增不良、胸前导联/肢体导联低电压,提示可能与心肌损伤程度有关。对于出现异常心电图表现的COVID-19患者尤其是重症患者,应密切关注心电图变化,预防不良心脏事件的发生。“,”Objective:To evaluate the abnormalities of body surface electrocardiogram in hospitalized patients with COVID-19.Methods:One hundred and forty-seven COVID-19 patients hospitalized in Zhongnan Hospital of Wuhan University from January 20, 2020 to March 1, 2020 were included. Based on the clinical classification, these patients were classified into two groups: mild/common group and critical/severe group. Demographic, laboratory data and body surface electrocardiogram were compared between the two groups.Results:One hundred and forty-seven COVID-19 patients (24 in critical/severe group and 123 in mild/common group) were finally included in this study. Compared with those in mild/common group, critical/severe group were older and in higher levels of markers of inflammation and myocardial enzyme. Moreover, ventricular premature beat (16.7% vs. 4.7%) , QTc prolongation (4.2% vs. 0) , equipotential Q wave (4.2% vs. 0) , poor R wave progression in the precordial leads (4.2% vs. 0) and low-voltage in limb/chest leads (9.1% vs. 0) were more frequent in critical/severe group than in mild/common group.Conclusion:Abnormal body surface electrocardiograms including ventricular premature beats, QTc prolongation, abnormal Q wave, poor R wave progression in the precordial leads and low-voltage in limb/chest leads were more frequent in critical/severe COVID-19 patients, which could be related to the degree of myocardial damage, indicating close attention should be paid to the changes of electrocardiograms in critical/severe COVID-19 patients to prevent adverse cardiac events.
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