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目的评价体部伽玛刀治疗老年腹膜后淋巴结转移癌的近期疗效。方法 107例老年腹膜后淋巴结转移癌采用OUR-QGD型立体定向伽玛刀治疗系统,50%~70%等剂量曲线包绕靶区边缘,靶区周边总剂量3500~5000 cGy,单次剂量260~500 cGy,每周照射3~5次。结果体部伽玛刀治疗腹膜后转移癌的RR83.2%,1、2、3年生存率分别为67.9%、34.2%、8.9%。放疗后NRS疼痛强度明显下降,Karnofsky评分显著升高。结论体部伽玛刀治疗老年腹膜后转移癌近期疗效好、临床症状缓解明显、副作用小,可作为治疗首选。
Objective To evaluate the short-term curative effect of body gamma knife in the treatment of elderly patients with retroperitoneal lymph node metastasis. Methods 107 elderly patients with retroperitoneal lymph node metastasis were treated with OUR-QGD stereotaxic gamma knife. The isodose curves of 50% ~ 70% were wound around the edge of the target. The total dose around the target was 3500 ~ 5000 cGy. The single dose of 260 ~ 500 cGy, weekly irradiation 3 ~ 5 times. Results Body gamma knife treatment of retroperitoneal carcinoma of the RR83.2%, 1, 2, 3-year survival rates were 67.9%, 34.2%, 8.9%. NRS pain intensity decreased significantly after radiotherapy, Karnofsky score was significantly increased. Conclusion Gamma knife treatment of retroperitoneal metastasis in elderly patients with short-term curative effect, obvious clinical symptoms, side effects, can be used as the treatment of choice.