三氮唑核苷(Ribavirin, 病毒唑,利巴韦林,以下简称Rbv)注射液是广谱抗病毒药,对多种病毒,如疱疹病毒、痘病毒、流感病毒、鼻病毒等均有明显抑制作用。临床上主要用于以上病毒引起的感染。随着临床的广泛使用,其不良反应日趋增多,应引起医务人员的重视。本文对1990～1997年文献报道有关Rbv的55例不良反应进行了统计分类,其中过敏、过敏性休克20例占36.4％;心血管系统6例占10.9％;消化系统5例占9.1％;血液系统20例占36.4％;神经系统3例占5.4％;急性肾功能衰竭1例占1.8％。 1 不良反应的类型及临床表现 Ribavirin (ribavirin, ribavirin, hereinafter referred to as Rbv) injection is a broad-spectrum antiviral drugs, a variety of viruses, such as herpes virus, pox virus, influenza virus, rhinovirus, etc. were significantly Inhibition. Clinically mainly used for the virus caused by the infection. With the widespread use of clinical, its adverse reactions are increasing, should be caused by medical personnel’s attention. In this paper, 55 cases of Rbv adverse reactions reported in the literature from 1990 to 1997 were statistically classified, of which allergic, anaphylactic shock in 20 cases accounted for 36.4%; cardiovascular system in 6 cases accounted for 10.9%; digestive system in 5 cases accounted for 9.1%; blood System 20 cases accounted for 36.4%; 3 cases of nervous system accounted for 5.4%; 1 case of acute renal failure accounted for 1.8%. A type of adverse reactions and clinical manifestations