目的为进一步了解食用盐碘含量变化对丹东沿海地区甲亢发病的影响,探索在沿海地区既能确保持续消除碘缺乏病,又能降低甲亢发病率的具体办法,指导碘缺乏病防治工作。方法通过查阅2000~2007年丹东市疾控中心甲状腺疾病门诊病历,调查甲亢发病率,并与历年碘缺乏病监测数据进行对比。结果2000~2007年盐碘浓度由46.2 mg/kg降至29.94 mg/kg,合格碘盐食用率由83.60%升高至98.14%,8~10岁儿童尿碘中位数均超过了200μg/L,同时期甲亢患者发病率呈先升高、后下降的趋势,平均发病率为0.031%,但仍维持在较高水平。结论不同地区应实行不同的食盐加碘标准,即山区实行食盐加碘,沿海地区食用低浓度碘盐或非碘盐,以降低甲亢的发病率。 Objective To further understand the influence of iodine content in edible salt on the incidence of hyperthyroidism in coastal areas of Dandong and to explore specific ways to ensure the continuous elimination of iodine deficiency disorders and reduce the incidence of hyperthyroidism in coastal areas and to guide the prevention and treatment of iodine deficiency disorders. Methods The medical records of thyroid disease in Dandong CDC from 2000 to 2007 were investigated, and the incidence of hyperthyroidism was investigated. The data were compared with the monitoring data of iodine deficiency disorders over the years. Results The salt iodine concentration decreased from 46.2 mg / kg to 29.94 mg / kg from 2000 to 2007, and the consumption of qualified iodized salt increased from 83.60% to 98.14%. The median urinary iodine of children aged 8-10 years exceeded 200 μg / L , While the incidence of hyperthyroidism was first increased, then decreased, with an average incidence of 0.031%, but still maintained at a high level. Conclusion Different regions should adopt different salt iodization standards, that is, salt iodization in mountainous areas and low concentration of iodized salt or non-iodized salt in coastal areas should be taken to reduce the incidence of hyperthyroidism.