论文部分内容阅读
目的：探索新的、有效的治疗阿米巴肝脓肿的药物。方法：诺氟沙星０．３－０．４９，ｔｉｄ，ｐｏ×１５ｄ，治疗３０例（男性２２例，女性８例；年龄４５±ｓ３ａ）阿米巴肝脓肿病人。用０．５％甲硝唑１００ｍＬ静脉滴注（静滴），ｂｉｄ×（３－５）ｄ，以后改为０．４ｇ，ｔｉｄ，ｐｏ×（７－１０）ｄ治疗２９例作对照。２组合并细菌感染者均加用四环素１．０ｇ，ｑｄ，静滴５－７ｄ或用氨苄西林２．０ｇ，ｔｉｄ，ｉｖ×（５－７）ｄ。结果：诺氟沙星组在治疗有效率，体温恢复正常时间，平均住院无数与甲硝唑组相似（Ｐ＞０．０５）。但脓腔缩小时间短，肝区疼痛消失早，不良反应少（Ｐ＜０．０１或０．０５）。结论：诺氟沙星治疗阿米巴肝脓肿优于甲硝唑。
Objective: To explore new and effective drugs for the treatment of amoebic liver abscess. Methods: Norfloxacin 0.3-0.49, tid, po × 15d, treatment of 30 patients (22 males and 8 females; age 45 ± s3a) patients with amoebic hepatic abscess. With 0.5% metronidazole 100mL intravenous infusion (intravenous infusion), bid × (3-5) d, later changed to 0.4g, tid, po × (7-10) d treatment of 29 cases as a control. 2 combined bacterial infection were added tetracycline 1.0g, qd, intravenous 5-7d or with ampicillin 2.0g, tid, iv × (5-7) d. Results: The norfloxacin group in the treatment of efficiency, body temperature returned to normal time, the average number of hospitalized metronidazole numerous (P> 0.05). However, shortening of abscess cavity, liver pain disappeared early, fewer adverse reactions (P <0.01 or 0.05). Conclusion: Norfloxacin is superior to metronidazole in the treatment of amoebic liver abscess.