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水苏(Stachys recta)的提取物水苏烯(Stachy-rene)制剂含多酚类化合物,具有利胆作用。本文进行了抗炎、解毒和降氮作用的实验研究。抗炎实验用甲醛或胰蛋白酶诱发的大白鼠足爪肿胀模型。在注入致炎剂前30分钟腹腔注射水苏烯500mg/kg结果表明,水苏烯具有明显抗炎作用,对甲醛组的抑制率为45.8±12.1%;对胰蛋白酶组的抑制率为42.4±4.6%。解毒实验用四氯化碳中毒兔进行。在中毒后的1,2,3,5,7,10和14天分别给予100ml/kg水苏烯,测定动物的肝功能。结果表明,用水苏烯治疗10天后谷丙
Stachys recta Extract Stachy-rene preparations contain polyphenolic compounds with choleretic properties. In this paper, an experimental study of anti-inflammatory, detoxification and nitrogen reduction was conducted. Anti-inflammatory experiment with rat paw swelling induced by formaldehyde or trypsin. The results showed that perylenetetraene 500 mg / kg was injected into the peritoneal cavity 30 minutes before injection of inflammatory agent. The results showed that the water threoene had obvious anti-inflammatory effect, the inhibition rate to formaldehyde group was 45.8 ± 12.1% and the inhibition rate to trypsin group was 42.4 ± 4.6%. Detoxification experiment with carbon tetrachloride poisoning rabbits. At 1, 2, 3, 5, 7, 10 and 14 days after poisoning, 100 ml / kg of water threoene was respectively administered to determine the liver function of the animals. The results showed that after treatment with water threoen alanya