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目的提高下呼吸道感染病人细菌培养阳性率及抗菌素的作用。方法对我院280例住院病人肘静脉血进行了常规与高渗同步培养的结果进行对照分析。结果分离出L型细菌67株,而常规培养均为阴性,阳性率提高了22.8%。分离菌种14种;以铜绿假单胞菌在各类标本中感染率占首位,20.89%;克雷伯杆菌属占第2位,16.42%,大肠杆菌、金黄色葡萄球菌占第3位,分别为11.94%、10.45%;其它各菌为肺炎链球菌、表皮葡萄球菌、阴沟肠杆菌、不动杆菌等均占有一定比例。对青霉素,头孢类抗生素高度抗药,对红霉素呈低度抗药,对亚胺培南、妥布霉素、万古霉素、头孢他定等敏感。结论采取常规与高渗同步培养可提高阳性率,为临床感染性疾病诊断和抗生素的合理使用提供了重要依据。
Objective To improve the positive rate of bacterial culture in patients with lower respiratory tract infection and the role of antibiotics. Methods 280 patients in our hospital elbow venous blood routine and hypertonic synchronous culture results were controlled. Results Sixty-seven strains of L-type bacteria were isolated, but all of them were negative in routine culture. The positive rate increased by 22.8%. Among them, 14 strains were isolated; the infection rate of Pseudomonas aeruginosa was the highest in all kinds of specimens, 20.89%; Klebsiella was the second, 16.42%, Escherichia coli, Staphylococcus aureus accounted for the third place, Respectively, 11.94%, 10.45%; other bacteria are Streptococcus pneumoniae, Staphylococcus epidermidis, Enterobacter cloacae, Acinetobacter and so occupy a certain proportion. For penicillin, cephalosporins highly resistant to erythromycin was low resistance, to imipenem, tobramycin, vancomycin, ceftazidime and other sensitive. Conclusion The routine and hypertonic synchronous culture can increase the positive rate, which provides an important basis for the diagnosis of clinical infectious diseases and the rational use of antibiotics.