原发性血小板增多症较少见。迄今,国内仅报道40余例。且未述及并发脑血栓,本文报告一例。病历摘要:男,52岁。1976年11月30日无何诱因突然出现上腹部绞痛;次日晨柏油便三次,约900克,急送某医院按上消化道出血治疗。半个月后,出血停止。上消化道钡透检查,胃及十二指肠未见病变。1977年以来曾在某些医院检查,血小板为79～120万/mm~3,余无异常。近一个月来说话不清、喝水呛、右侧肢体瘫、左侧肢体无力,于1979年4月入院。既往:近20年每于刷牙时齿龈出血,并有拔牙时出血不止史。无心血管疾患、外伤,感染及手术史。查体:体温36.5℃,脉搏80次/分,血压130/90mmHg。神志清,言语不利。皮肤及粘膜无出血点。浅表淋巴结无肿大。心肺无异常。肝肋缘下2.5cm,脾左肋缘下3cm,质中度硬,无触 Primary thrombocytosis less common. So far, only 40 cases reported in China. And did not mention concurrent cerebral thrombosis, this article reports a case. Medical record summary: Male, 52 years old. November 30, 1976 without any incentive sudden upper abdominal cramps; asphalt the next morning will be three times, about 900 grams, a hospital emergency delivery of upper gastrointestinal bleeding. Half a month later, bleeding stopped. Upper digestive tract barium examination, no lesions in the stomach and duodenum. Since 1977, some hospitals have been examined, platelets for 79 ~ 1.2 million / mm ~ 3, I was no exception. Nearly a month to speak unclear, drink choking, paralysis of the right limb, left limb weakness, admitted in April 1979. Past: Nearly 20 years, bleeding gums every time brushing teeth, and bleeding more than the history of tooth extraction. No cardiovascular disease, trauma, infection and surgery history. Physical examination: body temperature 36.5 ℃, pulse 80 beats / min, blood pressure 130 / 90mmHg. Conscious, negative words. Skin and mucous membrane without bleeding point. Superficial lymph nodes without swelling. No abnormal heart and lung. Under the liver margin of 2.5cm, spleen left margin of 3cm, medium hard, no touch