间位和对位氯代苯胺异构体是氯丙嗪、氯喹、利眠宁等药品的重要原料。生产上控制纯度多采用重氮化法的化学分析,它仅能测定三个异构体的总含量。由于邻、间、对位氯代苯胺的极性和沸点都极为相近,用一般的气相色谱固定相难以分离间、对氯代苯胺。 Henkel用Ucon oil(50-HB-2000或50-HB-5100)涂渍在用DMCS处理过的Text- The meta and para chloroaniline isomers are important raw materials for chlorpromazine, chloroquine, and chlordiazepoxide. Chemical control of the production of more use of diazotization method, which can only determine the total content of three isomers. As the o-, m-, p-chloroaniline polarity and boiling point are very similar, with the usual gas phase stationary phase is difficult to isolate, p-chloroaniline. Henkel was coated with Ucon oil (50-HB-2000 or 50-HB-5100) in a DMCS-treated Text-