颗粒细胞瘤(Granulsr cell tumor,GCT)是一种的良性肿瘤,多发生于舌,其次是发生于皮肤、皮下组织及消化道,也可发生于人体的其他部位。我们收集了6例颗粒细胞瘤,5例颗粒细胞瘤均显示典型的组织结特征,1例非典型颗粒细胞瘤显示肿瘤细胞大部分为梭形,细胞明显多形性,细胞内可见大量类圆形嗜伊红小球。结合病理组织形态学特征和免疫组化结果,并复习文献资料对其组织学形态特点、诊断标准和鉴别诊 Granuloma cell tumor (GCT) is a benign tumor that occurs mostly in the tongue, followed by the skin, subcutaneous tissue and the digestive tract, but also in other parts of the body. We collected 6 cases of granulosa cell tumor, 5 cases of granulosa cell tumor showed typical characteristics of tissue, 1 cases of atypical granulosa cell tumor showed most of the spindle cells, cells were pleomorphic, a large number of cells can be seen within the circle Shaped euphoria red ball. Combined histopathological features and immunohistochemical results, and review the literature on the histological features, diagnostic criteria and differential diagnosis