自1983年Mazur和Clark首次提出胃肠道间质瘤(gas-trointestinal stromal tumor,GIST)概念以来,其病理机制和生物学特性已渐趋明朗。大多数GIST发生于消化道内,早期症状隐匿,并具有潜在恶性特点,故内镜检查在其诊断中起着重要作用;而由于多种内镜下治疗技术的出现,已经形成较多内镜下治疗方法,包括结合腹腔镜的联合治疗技术。 Since the first concept of gastrointestinal stromal tumor (GIST) was first proposed by Mazur and Clark in 1983, the pathological mechanism and biological characteristics have gradually become clear. Most of the GIST occurs in the digestive tract, the early symptoms of occult and has potentially malignant characteristics, so endoscopy plays an important role in the diagnosis; and due to the emergence of a variety of endoscopic treatment techniques, have been more endoscopic Treatment options include combination therapy with laparoscopy.