前列腺癌(prostatic carcinoma,PCa)是男性生殖系最常见的恶性肿瘤,发病率随年龄的增长而提高。男性一生中患PCa的概率为16%,但只有3%的患者死于PCa[1]。因此PCa治疗的主要难题是如何从相对惰性的PCa患者中找出具有威胁性的部分,从而制定有针对性的治疗方案,使PCa的治疗具有个性化的特点。 Prostatic carcinoma (PCa) is the most common malignant tumor of the male reproductive system, the incidence increases with age. Men have a 16% chance of developing PCa in their lifetime, but only 3% of them die of PCa [1]. Therefore, the main challenge of PCa treatment is how to find out the threatening parts from the relatively inert PCa patients so as to formulate the targeted treatment plan and make the treatment of PCa personalized.