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植物中萜类化合物的抗肿瘤作用,近年来引起国内外的重视。国外曾报道,单萜类芳樟醇、香叶醇对Hela、KB细胞有中等毒性作用、香叶醇对小鸡淋巴瘤有40%的治愈率;临床用于手术及放射治疗后的肿瘤病人,在个别病例中取得较满意的结果。倍半萜以上的萜类化合物的抗肿瘤活性已有很多报道。我国进行的莪术挥发油及冬凌草抗肿瘤的研究,其中活性成份均为萜类化合物。
The anti-tumor effects of terpenoids in plants have attracted attention at home and abroad in recent years. It has been reported abroad that monoterpene linalool and geraniol have moderate toxic effects on Hela and KB cells, and geraniol has a 40% cure rate on chick lymphoma; clinically used tumor patients after surgery and radiation therapy , Obtained satisfactory results in individual cases. The antitumor activity of terpenoids above sesquiterpenes has been reported. Studies on the anti-tumor effects of Curcuma volatile oil and Rabdosia rubescens carried out in China, in which the active ingredients are terpenoids.