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目的:分析不同质量精子对卵胞浆内单精子注射(ICSI)治疗结局的影响。方法:2000年8月～2007年12月在柳州市妇幼保健院生殖健康助孕中心进行ICSI治疗的352例患者根据精子质量分为睾丸细针穿刺抽吸精子(TESE)组(134例)、严重少弱畸精子组(148例)、精液正常组(70例)。比较3组的受精率、种植率、优胚率、临床妊娠率、流产率、异位妊娠率、分娩率、单胎分娩率、双胎分娩率、早产率和出生缺陷率。结果:3组的受精率、种植率、临床妊娠率、流产率、异位妊娠率、分娩率、单胎分娩率、双胎分娩率、早产率和出生缺陷率比较差异无统计学意义(P>0.05),但在优胚率方面比较差异有统计学意义(P<0.05)。结论:不同质量精子不影响ICSI治疗结局。
Objective: To analyze the effect of different sperm quality on the intracytoplasmic sperm injection (ICSI) treatment outcome. Methods: From August 2000 to December 2007, 352 patients who underwent ICSI in Reproductive Health Center of Reproductive Health, Maternal and Child Health Care Hospital of Liuzhou City were divided into TESE group (134 cases) according to sperm mass, Severe oligozoospermia group (148 cases), normal semen group (70 cases). The fertilization rate, implantation rate, excellent embryo rate, clinical pregnancy rate, miscarriage rate, ectopic pregnancy rate, delivery rate, single birth rate, twins delivery rate, premature birth rate and birth defect rate were compared between the three groups. Results: There was no significant difference in fertilization rate, implantation rate, clinical pregnancy rate, abortion rate, ectopic pregnancy rate, delivery rate, single birth rate, twin birth rate, premature birth rate and birth defect rate in the three groups (P > 0.05), but the difference in excellent embryo rate was statistically significant (P <0.05). Conclusion: Different quality sperm do not affect ICSI treatment outcome.