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目的观察CT导引下电化学治疗对肝癌患者免疫功能的影响,探讨电化学能否改善患者的免疫功能。方法在CT导引下利用电化学疗法对36例肝癌患者进行了治疗,测定了治疗前后免疫参数:CD3+、CD4+、CD8+、CD4+/CD8+、NK、IgG、IgM、IgA,并将治疗前后2组数据分别进行对比。结果CD3+、CD4+、CD8+、CD4+/CD8+、NK等免疫参数明显升高,而IgG、IgM、IgA未发生明显变化。结论电化学疗法能增强肝癌患者的细胞免疫功能。
Objective To observe the effect of CT-guided electrochemical therapy on the immune function of patients with hepatocellular carcinoma (HCC) and to investigate whether electrochemical therapy can improve the immune function of patients. Methods Electrochemotherapy was used to treat 36 patients with hepatocellular carcinoma (HCC) under CT guidance. Immune parameters of CD3 +, CD4 +, CD8 +, CD4 + / CD8 +, NK, IgG, IgM and IgA were measured before and after treatment. Data were compared. Results The immune parameters such as CD3 +, CD4 +, CD8 +, CD4 + / CD8 + and NK were significantly increased, while no significant changes were observed in IgG, IgM and IgA. Conclusion Electrochemotherapy can enhance cellular immune function in patients with liver cancer.