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用哇巴因ｉｖ致豚鼠心律失常、乌头碱ｉｖ致大鼠心律失常、氯化钙－氯化乙酰胆碱ｉｖ致小鼠房颤、电刺激致家兔室颤、大鼠冠脉结扎诱发的心律失常等模型证实Ｎ－去甲基蝙蝠葛碱的具抗房性和室性心律失常作用，其作用剂量依赖性增强。离体试验表明Ｎ－去甲基蝙蝠葛碱浓度依赖性延长豚鼠乳头肌快反应和慢反应动作电位的ＡＰＤ５０、ＡＰＤ９０，降低ＡＰＡ，减慢Ｖｍａｘ。
Arrhythmias induced by ouabain iv in guinea pigs, arrhythmias in rats induced by aconitine iv, atrial fibrillation induced by calcium chloride-acetylcholine iv in mice, ventricular fibrillation induced by electrical stimulation in rabbits, and heart rhythms induced by coronary artery ligation in rats Models such as abnormalities confirmed the anti-atrial and ventricular arrhythmia effects of N-desmethyl batkaline, which was dose-dependently enhanced. Ex vivo tests showed that N-desmethylate dauricine concentration-dependently prolonged the APD50, APD90 of guinea pig papillary muscle fast response and slow response action potential, decreased APA, and slowed down Vmax.