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目的:比较高海拔地区与平原地区围绝经期妇女的骨密度(BMD)。方法:经DEXA确诊为骨质琉松的人群分为三组:高原地区(海拔4200m)围绝经期妇女180例为A组,年龄45岁～50岁,均为汉族,移居高原20余年。中度海拔地区(海拔2260m)围绝经期妇女180例为B组,年龄45岁～50岁,均为汉族,移居西宁地区20余年。平原地区(海拔40m)围绝经期妇女180例为C组,年龄同前,均为汉族,世居南京。采用法国DMS公司生产的CHRONOS型双能X线骨密度仪测定A组、B组和C组腰椎、大转子及股骨颈BMD。结果:A、B、C三组腰椎2～4、大转子、股骨颈BMD相比,无显著性差异(P>0.05)。结论:高海拔地区围绝经期妇女骨密度与平原地区无区别。
OBJECTIVE: To compare the bone mineral density (BMD) of perimenopausal women in high altitude and plain areas. Methods: The population diagnosed as DRG by DEXA was divided into three groups: 180 cases of perimenopausal women in plateau area (4200m above sea level) were A group, aged 45-50 years old, all Han nationality, migrating to plateau for more than 20 years. Mid-altitude areas (2260m above sea level) 180 cases of perimenopausal women as group B, aged 45 to 50 years old, all Han nationality, moved to Xining area more than 20 years. Plain area (elevation 40m) 180 cases of perimenopausal women as group C, the same age, are Han nationality, living in Nanjing. The BMD of lumbar vertebrae, greater trochanter and femoral neck in groups A, B and C were measured by CHRONOS dual energy X-ray absorptiometry. Results: There was no significant difference in the BMD of the lumbar vertebrae 2-4, the greater trochanter and the femoral neck in groups A, B and C (P> 0.05). Conclusion: There is no difference in bone mineral density between the perimenopausal women and the plain at high altitude.