论文部分内容阅读
对29例恶性组织细胞增生症(MH)的尸检材料,从病理形态、免疫组化及电镜超微结构三方面进行研究。发现MH病人胸腺萎缩,哈氏小体囊性变、钙化,提示病人伴有免疫功能缺陷。部分恶组细胞与α_1抗胰蛋白酶及溶菌酶反应,电镜下可见恶组细胞仍保持组织细胞的某些形态特征,支持恶组细胞起源于单核巨噬细胞系统的学说。赞成生前多部位反复骨髓穿刺检查,可能有助于提高生前诊断率。
29 cases of malignant histiocytosis (MH) autopsy material, from the pathological morphology, immunohistochemistry and electron microscopy three aspects of the study. MH patients found thymus atrophy, Hirschsprung’s cystic change, calcification, suggesting that patients with immune dysfunction. Some of the malignant cells reacted with α 1 antitrypsin and lysozyme, and some morphological features of the malignant cells were still observed under electron microscope. These cells supported the theory that the malignant cells originated from the mononuclear macrophage system. Pro-life multi-site repeated bone marrow biopsy, may help to improve the diagnosis of prenatal.