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目的探讨降钙素原(PCT)和C-反应蛋白(CRP)联合检测在新生儿败血症早期诊断中的价值。方法将45例新生儿败血症患者作为观察组,另选40例健康新生儿为对照组,检测并比较两组患儿血清PCT和CRP水平。结果观察组血清PCT、CRP水平明显高于对照组(P<0.05);观察组治疗前血清PCT、CRP水平明显高于恢复期和对照组(P<0.05)。结论 PCT和CRP可作为新生儿败血症早期诊断指标,并对病情的评估、治疗药物的选择和判断预后有一定临床作用,值得推广应用。
Objective To investigate the value of combined detection of procalcitonin (PCT) and C-reactive protein (CRP) in the early diagnosis of neonatal sepsis. Methods Forty-five neonates with sepsis were selected as the observation group and 40 healthy newborn controls as the control group. The levels of serum PCT and CRP in the two groups were detected and compared. Results The levels of serum PCT and CRP in the observation group were significantly higher than those in the control group (P <0.05). The levels of PCT and CRP in the observation group before treatment were significantly higher than those in the recovery and control groups (P <0.05). Conclusion PCT and CRP can be used as early diagnosis indicators of neonatal sepsis, and the clinical evaluation of the disease, the choice of treatment drugs and prognosis have some clinical significance, it is worth to promote the application.