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目的:探讨米非司酮配伍米索前列醇用于高危妊娠引产的临床疗效。方法:选择我院收治的高危妊娠孕妇150例,将所有患者随机分为2组,每组75例,观察组给予米非司酮配伍米索前列醇治疗,对照组给予依沙吖啶羊膜腔内注射治疗,比较2组孕妇的引产效果、胎盘排出时间、出血量及出血时间。结果:观察组引产成功率显著高于对照组,胎盘排出时间及阴道出血时间短于对照组,出血量低于对照组,差异均有统计学意义(P<0.05)。结论:米非司酮配伍米索前列醇用于高危妊娠引产,具有疗效显著、成功率高、损伤小等优点,值得临床推广应用。
Objective: To investigate the clinical efficacy of mifepristone combined with misoprostol for induction of labor during high-risk pregnancy. Methods: A total of 150 high-risk pregnant women were enrolled in our hospital. All patients were randomly divided into two groups (n = 75 each). The observation group was treated with mifepristone and misoprostol. The control group was given amrubicol Intra-injection therapy was compared between the two groups of pregnant women induction of labor, placental discharge time, bleeding and bleeding time. Results: The successful rate of induction of labor in the observation group was significantly higher than that of the control group. The time of placenta discharge and vaginal bleeding were shorter than that of the control group. The bleeding volume was lower than that of the control group. The difference was statistically significant (P <0.05). Conclusion: Mifepristone combined with misoprostol for induction of labor at high risk of pregnancy has the advantages of significant curative effect, high success rate and small injury. It is worthy of clinical application.