阻塞性肺病与早期中央型肺癌发病关系的研究

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目的探讨阻塞性肺病与中央型肺癌发病的关系。方法对652例胸部X射线呈现阻塞性肺病的肺癌高危者用螺旋CT、纤维支气管内窥镜、痰细胞学诊断、活检和手术切除等进行中央型肺癌筛查。结果确诊为中央型肺癌者64例,患病率为9.8%;其中阻塞性肺炎42例(占12.5%),阻塞性肺气肿14例(占8.4%),阻塞性肺不张8例(占5.3%);病理类型为鳞癌32例(占50.0%),小细胞癌18例(占28.1%),腺癌4例(占12.5%),其他6例(占9.4%)。结论阻塞性肺病与中央型肺癌的发病有关,重视筛查可提高肺癌的早期检出率。 Objective To investigate the relationship between obstructive pulmonary disease and the incidence of central lung cancer. Methods A total of 652 patients with lung cancer with chest X-ray presenting obstructive pulmonary disease were screened for central lung cancer with spiral CT, fibrobronchoscopy, sputum cytology, biopsy and surgical resection. The results were confirmed as 64 cases of central lung cancer, the prevalence was 9.8%; of which 42 cases of obstructive pneumonia (12.5%), obstructive pulmonary emphysema in 14 cases (8.4%), obstructive atelectasis in 8 cases Accounting for 5.3%). Pathological types were squamous cell carcinoma in 32 cases (50.0%), small cell carcinoma in 18 cases (28.1%), adenocarcinoma in 4 cases (12.5%) and other 6 cases (9.4%). Conclusions Obstructive pulmonary disease is associated with the development of central lung cancer. Emphasis on screening can improve the early detection rate of lung cancer.
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