扑热息痛（paracetamol）过量仍然是英国暴发性肝衰竭（FHF）的最常见原因，扑热息痛过量也是澳大尼亚FHF的重要原因。对于这类病人的处理，关键是要判断其是否必须行肝脏移植术。1989年，皇家医学院医院O’Grady等根据他们广博的经验提出两条有助于早期判断必需行肝移植术的标 Excess paracetamol remains the most common cause of fulminant hepatic failure (FHF) in the UK, and overdosing of paracetamol is also an important cause of FHF in Australia. The key to dealing with this type of patient is to determine whether it is necessary for a liver transplant. In 1989, O’Grady et al. Of the Royal College of Medicine Hospital put forward two pieces of evidence based on their extensive experience that would be helpful in early judging the need for liver transplantation