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周围神经损伤,平时战时均多见。据第二次世界大战战伤的一些统计,四肢神经伤约占外伤总数的10%,火器伤骨折中约有60%合并神经损伤。周围神经损伤后现在的主要治疗方法为非手术治疗及手术治疗,尤其是现代显微外科技术的发展,使周围神经修复的水平有了很大的提高。但周围神经损伤修复后的疗效仍不理想,因为影响周围神经的再生条件是非常多的。诞生于20世纪50年代的药物缓释的微囊化技术在制药及胰腺细胞、肝细胞的移植中,已得到较为广泛的应用,但其在周围神经损伤后修复中的应用比较少见。本文就微囊化技术及其在周围神经损伤后修复中的应用综述如下。
Peripheral nerve injury, usually more common in wartime. According to some statistics of the war wars in the Second World War, limb nerve injury accounts for about 10% of the total number of trauma and about 60% of the firearm injuries have nerve injury. Peripheral nerve injury is now the main treatment for non-surgical treatment and surgical treatment, especially the development of modern microsurgery technology, so that the level of peripheral nerve repair has been greatly improved. However, the efficacy of repaired peripheral nerve injury is still not ideal, because the regeneration of the conditions affecting the peripheral nerve is very large. The drug-releasing microencapsulation technology, which was born in the 1950s, has been widely used in pharmaceutical and pancreatic cells and hepatocyte transplantation. However, its application in the repair of peripheral nerve injury is relatively rare. This article on microencapsulation technology and its application in the repair of peripheral nerve injury are summarized below.