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近年来急性心肌梗塞(AMI)再灌注治疗已成为AMI的基本治疗方法。而再灌注后可出现心肌损伤加重和心功能减退与再灌注损伤。本研究对1995年1月~1997年6月收住确诊AMI25例,随机分为两组,Ⅰ组15例,用尿激酶与灯盏花05mg/kg静脉滴注。Ⅱ组10例为常规治疗对照。结果显示灯盏花组用药6h后T—SOD,2周后LVET明显高于对照组。提示在AMI溶栓时,应用灯盏花可减少氧自由基产生,减轻心肌再灌注损伤。
In recent years, acute myocardial infarction (AMI) reperfusion therapy has become the basic treatment of AMI. After reperfusion, there may be increased myocardial injury and cardiac dysfunction and reperfusion injury. This study from January 1995 to June 1997 admitted to confirm the diagnosis of AMI25 cases, were randomly divided into two groups, Ⅰ group of 15 cases, with urokinase and Erigeron 0 5mg / kg intravenous infusion. Ⅱ group of 10 cases of conventional treatment control. The results showed that the Etanercept group after 6h T-SOD, LVET was significantly higher than the control group after 2 weeks. Tip AMI thrombolysis, the application of Erigeron can reduce oxygen free radicals, reduce myocardial reperfusion injury.