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目的：观察侧孔注入式动注导管远端固定留置法预防肝动脉闭塞和消化道溃疡的效果，比较分析这种新的动注导管留置方法与传统的动注导管留置法及开腹直视下导管留置法的差异以及该方法尚存的问题。材料与方法：经左侧锁骨下动脉途径采用侧孔注入式动注导管远端固定留置法施行成功的１０４例转移性肝癌患者，留置术后随访期间１～９６周。结果：随访中确认肝动脉闭塞５例，发生率约５％，留置术后１周，经留置导管的核素９９ｍＴｃＭＡＡ扫描检查，７例消化道区域的核素聚集被显示，动注化疗过程随访中，经内窥镜检查确认胃溃疡３例，发生率约３％。结论：侧孔注入式动注导管远端固定留置法能明显降低肝动脉闭塞及消化道溃疡的发生率，是一种有效的预防和减少肝动脉闭塞及消化道合并症的方法。
OBJECTIVE: To observe the effectiveness of lateral hole-injected distally indwelling catheter for prevention of hepatic artery occlusion and peptic ulcer, and to compare and analyze this new method of injecting and injecting catheters, and traditional method of injecting and injecting catheters and open vision. The difference in catheter placement and the remaining problems with this method. Materials and Methods: One hundred and forty patients with metastatic liver cancer who underwent side-injection with a transfixion catheter were successfully performed through the left subclavian artery. The follow-up period was 1 to 96 weeks. Results: During follow-up, hepatic artery occlusion was confirmed in 5 cases, with an incidence of about 5%. After indwelling for 1 week, 99mTc-MAA scans of indwelling catheters were performed. Seven cases of nuclide accumulation in the digestive tract were displayed. During follow-up of the procedure, 3 cases of gastric ulcer were confirmed by endoscopy, and the incidence was about 3%. CONCLUSIONS: Lateral-hole-injected distally indwelling catheters can significantly reduce the incidence of hepatic artery occlusion and peptic ulcers. It is an effective method to prevent and reduce hepatic artery occlusion and gastrointestinal complications.