酚妥拉明强心甙治疗婴幼儿肺炎合并心衰50例临床观察

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酚妥拉明强心甙治疗婴幼儿肺炎合并心衰50例临床观察忻州地区人民医院(034000)张素芳,李润卿,潘振远,赵步青急性心力衰竭是婴幼儿肺炎的常见并发疗,血管活性药物协同强心甙治疗婴幼儿肺炎合并心力衰竭近年来已被临床应用,并收到显著效果,我院1988年12月至1991年3月对100例肺炎合并心衰的患儿分别采用强心甙常规治疗和加用酚妥拉明治疗,进行疗效对比观察,现将结果报告如下:对象和方法一、对象:观察对象100名随机分观察组与对照组各50例,两组在年龄和性别上有可比性。年龄:观察组平均年龄:14个月;对照组平均年龄:13个月。性别:观察组:男29例,女21例。男:女=1.4:1;对照组:男28例,女22例,男:女=1:3:1。全部病例均有典型支气管肺炎症状和体征,于入院时或入院后并发急性心衰,心衰诊断标准参照肺炎主要并发症临床诊断参考依据[1]。二、用药方法和剂量。两组患儿入院后均采用综合治疗(包括吸氧、抗菌素、镇静、利尿、止喘等药物),观察组加用酚妥拉明和强心甙联合治疗,对照组仅加用强心甙治疗,酚妥拉明每次0.3~0.5mg/kg,注于莫菲氏滴管静脉点滴,一般间隔2~4小时给药一次,病情好转后逐渐延长给药时间 Phentolamine cardiac glycosides in infants and young children with pulmonary heart disease 50 cases of clinical observation Xinzhou People’s Hospital (034000) Zhang Sufang, Li Runqing, Pan Zhenyuan, Zhao Buqiu Acute heart failure is common and concurrent treatment of pneumonia in infants and young children, vasoactive drugs synergistic cardiac Glycosides in infants with pneumonia complicated with heart failure in recent years has been clinically applied, and received significant results, our hospital from December 1988 to March 1991 on 100 cases of pneumonia with heart failure in children with conventional treatment of cardiac glycosides and Plus phentolamine treatment, the efficacy of comparative observation, the results are reported as follows: Subjects and methods 1, the object: the observation of 100 randomized observation group and control group of 50 patients, both groups were comparable in age and gender Sex. Age: The observation group average age: 14 months; control group average age: 13 months. Gender: Observation group: 29 males and 21 females. Male: female = 1.4: 1; control group: male 28, female 22, male: female = 1: 3: 1. All cases have typical symptoms and signs of bronchial pneumonia, admitted to hospital or admitted to hospital after acute heart failure, heart failure diagnostic criteria with reference to the main clinical diagnosis of pneumoconiosis reference [1]. Second, medication and dosage. The two groups of children were admitted to the hospital with a comprehensive treatment (including oxygen, antibiotics, sedation, diuretic, asthma and other drugs), the observation group plus phentolamine and cardiac glycosides combined treatment, the control group only with cardiac glycosides , Phentolamine each 0.3 ~ 0.5mg / kg, note the intravenous infusion of Murphy’s dropper, the general interval of 2 to 4 hours once administered, the condition improved gradually extended administration time
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