目的研究人参根和茎叶皂苷对孤独饲养小鼠自发运动及攻击行为的影响。方法小鼠孤独饲养4周后,分别以人参根及茎叶皂苷溶液灌胃,按高剂量100 mg.kg-1,低剂量25 mg.kg-1给药,并以生理盐水为空白对照,观察两者对小鼠自发运动及攻击行为的影响。结果人参根皂苷可减少小鼠的自发运动及攻击行为(P<0.01),人参茎叶皂苷可增加小鼠的自发运动及攻击行为。结论人参根皂苷具中枢镇静的功效,而人参茎叶皂苷作用相反。 Objective To study the effects of ginseng root, stem and leaf saponin on spontaneous motility and attack behavior in mice fed alone. Methods After 4 weeks of lonely feeding, the mice were gavaged with ginseng root and stem-leaf saponin solution respectively. The mice were dosed with high dose of 100 mg.kg-1 and low dose of 25 mg.kg-1, To observe the effect of both on spontaneous motility and attack behavior in mice. Results Ginseng root saponin can reduce the spontaneous movement and attack behavior of mice (P <0.01), ginseng stem and leaf saponin can increase spontaneous movement and attack behavior in mice. Conclusion Ginseng root saponin has the effect of central sedation, while the ginseng stem and leaf saponin has the opposite effect.