目的　贲门失弛缓症是原因不明的食管运动障碍性疾病 ,以食管缺乏蠕动和食管下括约肌松弛不良导致食道排空延迟为特征。为了明确病因 ,提高对可能的病因学的危险因素的认识 ,探讨其发病机制 ,我们进行了流行病学调查及回顾性分析。方法　选取并调查 1999年 4月～ 2 0 0 3年 6月 Aims Cardia achalasia is an unexplained esophageal motility disorder characterized by delayed esophageal emptying due to lack of esophageal motility and poor relaxation of the lower esophageal sphincter. In order to clarify the etiology, to raise awareness of the possible etiological risk factors and to explore its pathogenesis, we conducted epidemiological surveys and retrospective analyzes. Methods Select and survey from April 1999 to June 2003