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目的 :13 C 尿素呼气试验 (13 C UBT)检测幽门螺杆菌 (HP)感染并探讨与胃癌的关系。方法 :术前3天及手术后 10天对 5 3例胃癌病人进行13 C UBT检测并与 36例健康人群对照 ,以探讨胃癌病人HP的感染率。结果 :HP感染率健康对照组为 0 ,早期胃癌组为 75 .0 % ,中晚期胃癌组为 6 5 .8% (P <0 .0 5 )。结论 :HP感染是胃癌发生序列过程中的重要触发因子 ,在早期胃癌的发生中起重要作用。
OBJECTIVE: To evaluate the relationship between Helicobacter pylori (HP) infection and gastric cancer by 13 C urea breath test (13 C UBT). Methods: Fifty-three patients with gastric cancer underwent 13-C UBT detection 3 days before surgery and 10 days after surgery and compared with 36 healthy people to explore the prevalence of HP in patients with gastric cancer. Results: HP infection rate was 0 in healthy control group, 75.0% in early gastric cancer group, and 65.8% in advanced gastric cancer group (P <0.05). Conclusion: HP infection is an important trigger factor in the sequence of gastric cancer and plays an important role in the development of early gastric cancer.