原发性血小板减少性紫癜是一种常见的出血性疾病。其发病原因虽尚未完全明瞭,但目前认为主要与体液免疫有着密切的关系,患者的血清中存在着抗血小板抗体,它是一种免疫球蛋白(IgG),当这种抗体覆被于血小板表面时,血小板即易被脾或肝破坏而致存活时间缩短,并因而导致血小板减少。此外,细胞免疫异常亦可能与发病有关。根据临床经过的不同,本病分为急性型和慢性型两种类型,识别这两种类型对于判断预后和合理治疗均有重要意义。急性型多见于2～8岁小儿,男女发病数大致相等。患者常于发病前2～21天有急性感染病史,大多为病毒性感 Primary thrombocytopenic purpura is a common hemorrhagic disease. Although the cause of the disease is not yet fully understood, it is currently believed that there is a close relationship with humoral immunity. Antibody platelets are present in the serum of patients and are an immunoglobulin (IgG). When this antibody is coated on the platelet surface , Platelets are easily damaged by the spleen or liver resulting in shortened survival time and thus resulting in thrombocytopenia. In addition, cellular immune abnormalities may also be related to the pathogenesis. According to the different clinical experience, the disease is divided into two types of acute and chronic types, to identify these two types of prognosis and reasonable treatment are of great significance. Acute type more common in children aged 2 to 8, the number of male and female approximately equal. Patients often have a history of acute infection 2 to 21 days before onset, mostly virally