论文部分内容阅读
目的评价强化生活方式对农村代谢综合征(MS)患者的干预效果。方法从MS横断面调查研究中纳入253例MS患者,不完全随机分成干预组(182例)和常规管理组(71例)。干预组采用合理膳食、规律运动及健康教育为重点的强化生活方式进行干预;常规管理组按慢性病管理工作规范和程序进行管理。干预6个月后比较干预前后MS患者体格指标及代谢相关生化指标差异。结果两组MS患者体格指标和代谢相关生化指标基线水平差异均无统计学意义(P>0.05)。干预6个月后,干预组和常规管理组MS患病率分别为67.14%和60.95%,差异无统计学意义(P>0.05)。干预组体重、BMI、腰围分别下降3.11 kg、1.50 kg/m~2、4.29 cm,常规管理组分别下降1.23 kg、0.47 kg/m~2、1.22 cm,差异均有统计学意义(P<0.01)。干预组尿酸(UA)、三酰甘油(TG)分别减少14.30μmol/L、0.01 mmol/L,常规管理组分别增加18.17μmol/L、0.41 mmol/L,差异均有统计学意义(P<0.05)。干预组高密度脂蛋白胆固醇(HDL-C)增加0.02 mmol/L,常规管理组减少0.10 mmol/L,差异有统计学意义(P<0.01)。干预组中高依从性组体重、BMI分别减少3.93 kg、1.40 kg/m~2,低依从性组分别减少2.80 kg、1.00 kg/m~2;高依从性组体脂率(BF%)减少2.27%,低依从性组增加1.01%,差异均有统计学意义(P<0.05)。结论强化生活方式干预可有效改善农村居民MS代谢组分异常状况。
Objective To evaluate the intervention effect of intensive life style on rural patients with metabolic syndrome (MS). Methods A total of 253 patients with MS were included in the MS cross-sectional study and were not randomly assigned to intervention group (n = 182) and conventional management group (n = 71). The intervention group intervened by the way of strengthening lifestyles with reasonable diet, regular exercise and health education. The routine management group was managed according to the chronic disease management practices and procedures. Six months after the intervention, MS patients before and after intervention compared physical indicators and metabolic-related biochemical differences. Results There was no significant difference in the baseline level of biochemical indexes and metabolic index between the two groups of MS patients (P> 0.05). Six months after the intervention, the prevalence of MS was 67.14% and 60.95% in intervention group and routine management group, respectively, with no significant difference (P> 0.05). The body weight, BMI and waist circumference of the intervention group decreased by 3.11 kg and 1.50 kg / m ~ 2, 4.29 cm, respectively, but decreased by 1.23 kg and 0.47 kg / m ~ 2 and 1.22 cm respectively in the conventional management group (P <0.01) ). The levels of uric acid (UA) and triglyceride (TG) in the intervention group decreased by 14.30 μmol / L and 0.01 mmol / L, respectively, while those in the conventional management group increased by 18.17 μmol / L and 0.41 mmol / L, ). The intervention group HDL-C increased 0.02 mmol / L, conventional management group decreased 0.10 mmol / L, the difference was statistically significant (P <0.01). In the intervention group, body weight and BMI were decreased by 3.93 kg and 1.40 kg / m ~ 2, respectively, while those in the low compliance group were decreased by 2.80 kg and 1.00 kg / m ~ 2 respectively; BFR of high compliance group was decreased by 2.27% %, Low compliance group increased 1.01%, the difference was statistically significant (P <0.05). Conclusion Intensive life style intervention can effectively improve the abnormal status of MS metabolites in rural residents.