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用静水式试验方法评价和比较了两种钻井泥浆的水可溶部份对斑节对虾仔虾、罗氏沼虾仔虾、虾虎鱼和剑尾鱼等4种水生动物的急性毒性。结果表明：泥浆水溶性成分对班节对虾仔虾、罗氏沼虾仔虾、虾虎鱼和剑尾鱼的半数致死浓度均明显大于10000mg／L（1％），但斑节对虾仔虾对泥浆水可溶性成份的敏感性高于其余3种动物，适于钻井泥浆毒性试验。可以认为在试验条件下两种泥浆是无急性毒性的物质，但由于泥浆组成的复杂性，综合评价泥浆对水环境的影响时，需探讨其对底栖生物的影响。
Acute water test was used to evaluate and compare the acute toxicity of water-soluble fractions from two drilling muds to four aquatic animals, such as Penaeus monodon, Macrobrachium rosenbergii, goby and swordtail fish. The results showed that the half-lethal concentration of water-soluble components of muddy shrimp was significantly higher than that of 10000mg / L (1%) of Penaeus vannamei, Macrobrachium rosenbergii, Water-soluble ingredients are more sensitive than the other three animals and are suitable for drilling mud toxicity testing. However, due to the complexity of the mud composition, it is necessary to investigate the influence of the mud on the benthic organisms when comprehensively evaluating the impact of the mud on the water environment.