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目的探讨胰岛素强化治疗糖尿病合并进展型脑梗死的血糖水平及临床疗效分析。方法选取2012年3月至2014年3月在高州市第二人民医院住院的患者100例,随机分为对照组和治疗组,治疗组在常规给予抗凝、抗血小板、自由基清除剂、降血脂、脱水、改善循环、脑保护等基础上给予三餐前普通胰岛素+晚睡前甘精胰岛素强化治疗,血糖水平控制在基本正常水平(4.5~6.7 mmol/L);对照组只给予三餐前普通胰岛素控制血糖,血糖控制在8~11.1 mmol/L间,其他治疗同治疗组。观察两组治疗2周、4周后的血糖水平、神经功能缺损评分、日常生活能力评分等临床疗效指标。结果两组患者治疗2周、4周后血糖水平、神经功能缺损评分、日常生活能力评分差异均有统计学意义(P<0.05),治疗组优于对照组。结论胰岛素强化治疗能更好地控制糖尿病合并进展型脑梗死患者的血糖水平,降低血黏度,改善神经功能缺损及日常生活能力,有助于改善患者的预后。
Objective To investigate the effects of insulin therapy on blood glucose levels in patients with diabetes mellitus complicated with progressive cerebral infarction. Methods A total of 100 hospitalized patients in the Second People’s Hospital of Gaozhou from March 2012 to March 2014 were randomly divided into control group and treatment group. The patients in the treatment group were given anticoagulant, antiplatelet, free radical scavenger, Blood glucose, dehydration, improve circulation, brain protection based on the normal insulin before meals + intensive insulin glancing before going to sleep, blood glucose levels were controlled at a basic level of normal (4.5 ~ 6.7 mmol / L); control group only given three meals Before normal insulin control blood sugar, blood sugar control in 8 ~ 11.1 mmol / L, other treatment with the treatment group. Two groups were observed for 2 weeks, 4 weeks after the blood glucose level, neurological deficit score, daily living ability score clinical efficacy indicators. Results The two groups of patients were treated for 2 weeks, 4 weeks after the blood glucose level, neurological deficit score, daily living ability score differences were statistically significant (P <0.05), the treatment group was better than the control group. CONCLUSION: Intensive insulin therapy can better control blood glucose level, reduce blood viscosity, improve neurological deficits and daily living ability in patients with diabetes mellitus complicated with progressive cerebral infarction and improve prognosis.